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Lineage tracing: technology tool for exploring the development ...
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01941-y#:~:text=Lineage%20tracing%20is%20the%20most%20widely%20used%20technique,progression%20by%20tracing%20the%20fates%20of%20individual%20cells.
Cell lineage - Wikipedia
https://en.wikipedia.org/wiki/Cell_lineage
Lineage tracing - PubMed
https://pubmed.ncbi.nlm.nih.gov/22265400/
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19 (th) century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. Lineage tracing provides a powerful means of understanding tissue ...
Cell lineage Definition & Meaning - Merriam-Webster
https://www.merriam-webster.com/dictionary/cell%20lineage
Definition of cell lineage. : the developmental history of a cell from the first cleavage division until its ultimate fate is determined.
Lineage tracing: technology tool for exploring the …
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01941-y
Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue injury repairing, and tumor progression by tracing the fates of individual cells.
Lineage tracing meets single-cell omics: opportunities …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307462/
Traditionally reliant on microscopy, lineage-tracing approaches have recently evolved to allow the tracking of cell clones via sequencing of inherited DNA sequences, or ‘barcodes’. The migration to sequencing platforms has brought several advantages to lineage-tracing efforts: massive throughput, multiplexing and compatibility with other sequencing-based measurements (for …
Lineage tracking - Latest research and news | Nature
https://www.nature.com/subjects/lineage-tracking
Lineage tracking Definition. Lineage tracking methods follow the position and behaviour of cells and their descendents over time.
Tracing the lineage of tracing cell lineages | Nature Cell …
https://www.nature.com/articles/ncb0901-e216
It requires the identification of a cell or group of cells and of all of their descendants during embryonic development.
Concepts of cell lineage in mammalian embryos - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793410/
In theory, tracing cell lineage in an embryo is simple: find some means of marking a cell without disturbing the embryo and then keep track of the marked cell and its descendents as the embryo develops to see where they go. ... But with this type of study, the concept of cell lineage shifts slightly as the definition of the cell type being ...
Theory and Practice of Lineage Tracing - HSU Laboratory
http://hsulaboratory.org/wp-content/uploads/2018/07/hsu-2015-stem_cells.pdf
Lineage tracing is a method that delineates all progeny produced by a single cell or a group of cells. The possibility of performing lineage tracing initiated the field of Developmental Biology
Lineage tracing reveals the phylodynamics, plasticity, and …
https://www.cell.com/cell/fulltext/S0092-8674(22)00462-7
Yang et al. developed a genetically engineered mouse model of lung cancer capable of continuous lineage tracing with single-cell RNA-seq readout. They identified the subclonal dynamics of tumors, gene modules underlying expansion, transient increases in cellular plasticity, stereotypical evolutionary paths to aggressiveness across tumor genotypes, and the …
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