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Improving the Usability of Virtual Reality Neuron Tracing …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891492/
    The DIADEM metric accounts for the length and topology of a trace, scoring how well a trace captures the branching structure of a neuron on a scale of 0 (dissimilar) to 1 (identical). The score is penalized for missing branches, excess branches, incorrectly placed branches, and differences in branch length (see Figure 9 ).

Neuronal tracing - Wikipedia

    https://en.wikipedia.org/wiki/Neuronal_tracing
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The DIADEM metric: comparing multiple reconstructions …

    https://pubmed.ncbi.nlm.nih.gov/21519813/
    The DIADEM metric was specifically designed to capture the most critical aspects in automating neuronal reconstructions, and can function in feedback loops during algorithm development. During the Challenge, the metric scored the automated reconstructions of best-performing algorithms against manually traced gold standards over a representative ...

Automated Neuron Tracing Methods: An Updated Account

    https://link.springer.com/article/10.1007/s12021-016-9310-0
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Automated 3-D Neuron Tracing With Precise Branch …

    https://pubmed.ncbi.nlm.nih.gov/29993997/
    In this paper, we developed a new algorithm for automatic 3-D neuron reconstruction. The main idea of the proposed algorithm is to iteratively track backward from the potential neuronal termini to the soma centre. An online confidence score is computed to decide if a tracing iteration should be stopped and discarded from the final reconstruction.

APP2: automatic tracing of 3D neuron morphology based …

    https://academic.oup.com/bioinformatics/article/29/11/1448/220823
    Motivation: Tracing of neuron morphology is an essential technique in computational neuroscience. However, despite a number of existing methods, few o ... The authors thank DIADEM, Giorgio Ascoli, Greg Jefferies, Ann-Shyn Chiang, Paloma Gonzalez Bellido and Gerry Rubin for providing the testing image data used in this article and many ...

DeepNeuron : an open deep learning toolbox for neuron …

    https://braininformatics.springeropen.com/articles/10.1186/s40708-018-0081-2
    A number of manual/semiautomatic neuron tracing software packages in both the public domain and commercial world have been developed [1,2,3,4,5,6,7,8,9]. To further promote the development of neuron tracing tools, the DIADEM challenge and the BigNeuron project were launched to compare different automated algorithms. At small or medium scales ...

From DIADEM to BigNeuron

    https://pure.eur.nl/ws/portalfiles/portal/47700264/REPUB_88663_OA.pdf
    Neuron reconstruction methods have evolved over the last 100 years from the 2D hand drawings by Ramón y Cajal and his contemporaries to quantitative tracing of neuron morphologies in 3D with the help of computers. To this day, manual tracing is still the prevailing method even for 3D reconstruction.2 However, manual ap-

A Broadly Applicable 3-D Neuron Tracing Method …

    https://www.researchgate.net/profile/Badrinath-Roysam/publication/50377555_A_Broadly_Applicable_3-D_Neuron_Tracing_Method_Based_on_Open-Curve_Snake/links/54f089fa0cf2b36214aa5468/A-Broadly-Applicable-3-D-Neuron-Tracing-Method-Based-on-Open-Curve-Snake.pdf
    DIADEM challenge. Keywords Automated neuron tracing.Open-curve snake. Axon reconstruction.Gradient vector flow.Radius estimation Introduction Highly automated and robustly scalable computational tools

Exploring highly reliable substructures in auto …

    https://braininformatics.springeropen.com/articles/10.1186/s40708-021-00137-1
    The digital reconstruction of a neuron is the most direct and effective way to investigate its morphology. Many automatic neuron tracing methods have been proposed, but without manual check it is difficult to know whether a reconstruction or which substructure in a reconstruction is accurate. For a neuron’s reconstructions generated by multiple automatic …

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