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[Studies on neuronal tracing with pseudorabies virus]
https://pubmed.ncbi.nlm.nih.gov/25118391/
With its abilities of trans-synaptic tracing and self-replication and wide host range, pseudorabies virus (PRV) has been applied in the field of neuroanatomy since the 1970s. Four decades of PRV application have made many advances in researches on neuronal tracing with PRV. Mechanism studies focused on investigating infection of primary neurons and tracing direction in …
Pseudorabies virus tracing of neural pathways between the ...
https://pubmed.ncbi.nlm.nih.gov/10713575/
The transneuronal tracer, pseudorabies virus (PRV), was used to identify pathways from the uterine cervix which may be involved in induction of analgesia and abbreviation of estrus by vaginocervical stimulation. In Experiment I, PRV immunoreactivity (PRV-IR) in brain and spinal cord was examined 3-5 days after injection into the cervix of ovariectomized (OVX) female rats …
Transneuronal Circuit Analysis with Pseudorabies Viruses - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165084/
Pseudorabies virus and the functional architecture of the ...
https://pubmed.ncbi.nlm.nih.gov/11106062/
Transneuronal tracing of neuronal circuitry with neurotropic viruses has provided valuable insights in the way in which the nervous system imposes temporal organization on physiological processes and behavior. The swine alpha herpes virus known as pseudorabies virus, or PRV, has been particularly useful in this regard.
Molecular Biology of Pseudorabies Virus: Impact on ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1197806/
The route of pseudorabies virus propagation in the mouse nervous system follows intranasal inoculation as described . The infection spreads through three neuronal pathways innervating the nasal cavity: (i) via anterograde spread in the trigeminal circuit, from trigeminal ganglia to spinal trigeminal nucleus, (ii) via retrograde spread in the sympathetic circuit, from superior cervical …
Transneuronal circuit analysis with pseudorabies viruses
https://pubmed.ncbi.nlm.nih.gov/18428451/
Transneuronal circuit analysis with pseudorabies viruses. Over the past decade there has been a dramatic increase in the use of viruses as transneuronal tracers of neuronal circuitry. The method exploits the propensity of neurotropic viruses to invade neurons and then produce infectious progeny that cross synapses to infect other neurons within a circuit. ….
Viral neuronal tracing - Wikipedia
https://en.wikipedia.org/wiki/Viral_Neuronal_Tracing
A PC12 neuron infected with pseudorabies virus PRV GS443 (labeled in green). The green dots moving away from the cell body demonstrates anterograde transport . Viral neuronal tracing is the use of a virus to trace neural pathways , providing a self-replicating tracer .
Molecular biology of pseudorabies virus: impact on ...
https://pubmed.ncbi.nlm.nih.gov/16148307/
Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae subfamily, and the etiological agent of Aujeszky's disease. This review describes the contributions of PRV research to herpesvirus biology, neurobiology, and viral pathogenesis by focusing on (i) the molecular biology of PRV, (ii) model systems to study PRV pathogenesis and …
Dual-Pseudorabies Viral Tracing for Spinal Tyrosine ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742299/
Transsynaptic Tracing from Peripheral Targets with ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692604/
Transsynaptic tracing has become a powerful tool used to analyze central efferents that regulate peripheral targets through multi-synaptic circuits. This approach has been most extensively used in the brain by utilizing the swine pathogen pseudorabies virus (PRV) 1. PRV does not infect great apes, including humans, so it is most commonly used in studies on …
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