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Glucose metabolism and recycling of radioactively …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1161515/
The glucose metabolism of conscious lean and obese rats of the Zucker strain was studied by using doubly labelled glucose ([6-3H,U-14C]glucose) given by intravenous injection as a single dose. ... [14C]-glucose after passing through the pyruvate pool in the two groups of rats if the rate of recycling of radioactivity (Rc) was expressed as a ...
RADIOACTIVE carbon studies of glucose metabolism in ...
https://pubmed.ncbi.nlm.nih.gov/13335032/
RADIOACTIVE carbon studies of glucose metabolism in diabetes. ... RADIOACTIVE carbon studies of glucose metabolism in diabetes Nutr Rev. 1956 Jul;14(7):196-7. doi: 10.1111/j.1753-4887.1956.tb01568.x. PMID: 13335032 DOI: 10.1111/j.1753-4887.1956.tb01568.x No abstract available. MeSH terms Carbohydrate Metabolism* ...
A computer program for tracing radioactivity in complex ...
https://www.ncbi.nlm.nih.gov/pubmed/5602832
1. Comput Biomed Res. 1967 Jul;1(2):139-45. A computer program for tracing radioactivity in complex metabolic systems. Haut M, Basickes S. PMID:
Isotope Tracing Untargeted Metabolomics Reveals …
https://pubmed.ncbi.nlm.nih.gov/30448730/
Labeling from [13 C]glucose is competed by unlabeled fatty acids and acetoacetate, underscoring the broad roles for substrate metabolism beyond energy conversion. Finally, the LPS-polarized macrophage metabolite itaconate is imported into IL-4-polarized macrophages, in which it reprograms [13 C]glucose metabolism. Thus, use of fully ...
Metabolic Profiling Using Stable Isotope Tracing Reveals ...
https://pubmed.ncbi.nlm.nih.gov/31747582/
Naive CD8<sup>+</sup> T cells differentiating into effector T cells increase glucose uptake and shift from quiescent to anabolic metabolism. Although much is known about the metabolism of cultured T cells, how T cells use nutrients during immune responses in vivo is less well defined. Here, we combi …
Metabolomics and isotope tracing - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034115/
Similarly in metabolism, a common cause of metabolite build-up is decreased consumption. For example, when glucose is removed from yeast, glycolytic efflux drops sharply, leading to build-up of lower glycolytic intermediates even though pathway influx is decreased (Figure 2B, Lowry et al, 1971). Because metabolite levels and fluxes provide ...
Tracing Cardiac Metabolism In Vivo: One Substrate at a ...
https://jnm.snmjournals.org/content/51/Supplement_1/80S
Progressive accumulation of glucose tracer analog 18 F-FDG by isolated working rat heart perfused with Krebs-Henseleit bicarbonate saline containing glucose (5 mM) as substrate. Input function (radioactivity in perfusate) was stable (lower curve). At 60 min, perfusate was switched to same saline without tracer analog (lower curve).
Mechanisms and Methods in Glucose Metabolism and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605583/
Abstract. Glucose metabolism represents a critical physiological program that not only provides energy to support cell proliferation, but also directly modulates signaling pathways of cell death. With the growing recognition of regulation of cell death by glucose metabolism, many techniques that can be applied in the study have been developed.
Metabolomics and Isotope Tracing - Cell
https://www.cell.com/cell/pdf/S0092-8674(18)30387-8.pdf
consume glucose, with cellulose the most abundant biopolymer on earth. Accordingly, around 100 high-flux compounds are consistently major metabolome constituents: amino acids, nu-cleotides, and intermediates of glycolysis, the pentose phos-phate pathway (PPP), and the TCA cycle. In contrast to the finite core of metabolism, the full scope of
Analysing central metabolism in ultra-high resolution: At ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056925/
The metabolism of glucose branches into multiple pathways and requires the analysis of the flux of carbon through central carbon metabolism: glycolysis, pentose phosphate pathway (PPP), TCA cycle, and amino acid metabolism. ... However, through [1,2– 13 C] glucose tracing, it has been observed that the non-oxidative pathway takes precedence ...
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